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Description

Promoter hypermethylation in cancer silences LDHB, eliminating lactate dehydrogenase isoenzymes 14

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Dosage: Typically, one session per week for 10 weeks

We need long-term follow-up data to confirm the promising roles of IBAT in changing the natural course of PFIC disease, such as the delay in the need for LT due to pruritus or end-stage liver disease